TBI-Traumatic Brain Injury & Alzheimer’s Disease

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Scientists have known for years that people who experience traumatic brain injury (TBI) are at greater risk for Alzheimer’s disease later in life. Now, new research published in Nature has not only found the mechanism by which TBI causes Alzheimer’s disease, but it has also uncovered a possible cure. Antibodies to the rescue! “Antibody technology is a popular drug development approach due to its extraordinary specificity and high success rate,” he said. “Moreover, the process to convert our current mouse antibody to one that can be tested in humans has been streamlined and can be done within a couple of years. Obviously, this will depend on funding.”explains Kun Ping Lu, M.D., Ph.D, professor of medicine at Harvard Medical School and chief of the Division of Translational Therapeutics at Beth Israel Deaconess Medical Center. Read this exciting trial on mice using a special antibody that could tag the problem protein, cis P-tau and keep it from spreading throughout the brain.

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